Resultados Liga MX
| enero 22, 2022 | ||
| Monterrey | 2 - 2 | Cruz Azul |
| Club América | 0 - 2 | Atlas |
| León | 2 - 1 | Pachuca |
| CD Guadalajara | 1 - 1 | Querétaro |
| enero 21, 2022 | ||
| Mazatlán | 1 - 2 | Toluca |
| enero 20, 2022 | ||
| Atlético San Luis | 0 - 1 | Juárez |
| enero 19, 2022 | ||
| León | 1 - 1 | Atlas |
| enero 16, 2022 | ||
| Pachuca | 2 - 1 | CD Guadalajara |
| Toluca | 3 - 1 | Santos Laguna |
| enero 15, 2022 | ||
| Club Tijuana | 1 - 1 | León |
| Cruz Azul | 1 - 0 | Juárez |
| Tigres de la UANL | 0 - 2 | Puebla |
| Atlas | 1 - 0 | Atlético San Luis |
| enero 14, 2022 | ||
| Necaxa | 0 - 4 | Monterrey |
| Querétaro | 1 - 3 | Pumas UNAM |
| enero 12, 2022 | ||
| Santos Laguna | 1 - 1 | Tigres de la UANL |
| enero 10, 2022 | ||
| Pumas UNAM | 5 - 0 | Toluca |
| enero 9, 2022 | ||
| CD Guadalajara | 3 - 0 | Mazatlán |
| enero 8, 2022 | ||
| Cruz Azul | 2 - 0 | Club Tijuana |
| Monterrey | 0 - 0 | Querétaro |